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Anaplastic Multiple Myeloma Presenting as Acute Liver Failure: A Case Report
Yasmin O Ali1, Khalid Ahmed2, Jason Eckmann3
1Department of Internal Medicine, Hennepin Healthcare, Minneapolis, Minnesota.
Gastro Hep Advances
|June 16, 2025
Summary
Anaplastic multiple myeloma (AMM) is a rare cancer. This case report details a patient with AMM affecting the liver, leading to acute liver failure, highlighting diagnostic challenges.
Area of Science:
- Oncology
- Hepatology
Background:
- Anaplastic multiple myeloma (AMM) is an aggressive subtype of multiple myeloma.
- Liver involvement in AMM is exceptionally rare and associated with poor treatment outcomes.
- Diagnosis is often delayed, with many cases identified postmortem.

