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Uncertainty estimation for dosimetry in radiation oncology
Wolfgang Lechner1, Hugo Palmans2,3
1Div. of Medical Physics, Department of Radiation Oncology, Medical University of Vienna, Vienna, Austria.
Physics and Imaging in Radiation Oncology
|June 16, 2025
Summary
Accurate dosimetry in radiation oncology relies on uncertainty assessment. This review clarifies uncertainty concepts and their application in radiation oncology for improved quality assurance.
Area of Science:
- Medical Physics
- Radiation Oncology
- Metrology
Background:
- Accurate dosimetry is crucial for effective cancer treatment.
- Uncertainty assessment in dose measurements is often neglected or poorly documented.
- Lack of standardized uncertainty reporting hinders result interpretation and quality assessment.
Purpose of the Study:
- To review and clarify concepts of uncertainty expression in radiation oncology.
- To provide practical examples of uncertainty assessment in clinical dosimetry.
- To guide the presentation and utilization of uncertainty budgets for quality assurance.
Main Methods:
- Review of fundamental uncertainty concepts (Type A, Type B, correlations).
- Introduction of advanced concepts like effective degrees of freedom.
- Application of these concepts to practical scenarios in radiation oncology.
Main Results:
- Comprehensive summary of uncertainty quantification methods.
- Illustrative examples demonstrating uncertainty assessment in practice.
- Guidance on presenting uncertainty budgets and establishing quality assurance limits.
Conclusions:
- Standardized uncertainty assessment is vital for reliable radiation dosimetry.
- Clear communication of uncertainties enhances the quality and trustworthiness of results.
- Effective use of uncertainty budgets improves quality assurance in radiation oncology.
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