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Hypoglycemic Hemiparesis Presenting as a Stroke Mimic: A Case Report
Joel Collins1, James Espinosa1, James Lee1
1Emergency Medicine, Jefferson Health, Stratford, USA.
Cureus
|June 17, 2025
Summary
Hypoglycemia can mimic stroke symptoms, presenting as hemiparesis and slurred speech. Prompt glucose level assessment is crucial for diagnosing and treating these stroke-like episodes in diabetic patients.
Area of Science:
- Neurology
- Endocrinology
- Emergency Medicine
Background:
- Diabetes Mellitus (DM) management requires careful monitoring of blood glucose levels.
- Stroke-like symptoms necessitate rapid differential diagnosis, including metabolic causes.
- Hypoglycemia can manifest with focal neurological deficits, mimicking cerebrovascular events.
Observation:
- A 47-year-old male with DM presented with acute right-sided hemiparesis and slurred speech.
- Initial blood glucose was critically low (37 mg/dL), with rapid symptom resolution after intravenous dextrose administration.
- Cranial imaging (CT head, CT angiogram, MRI brain) revealed no evidence of stroke.
Findings:
- The patient's presentation was diagnosed as hypoglycemic hemiplegia, a stroke-like condition caused by severe hypoglycemia.
- The etiology was attributed to missed meals and an excessive diabetes medication regimen.
- Recurrent hypoglycemia (blood sugar 60 mg/dL) required a second dextrose dose.
Implications:
- This case highlights the importance of including blood glucose assessment in stroke protocols.
- Early detection and management of hypoglycemia can prevent misdiagnosis and ensure timely treatment.
- Understanding hypoglycemia's potential to mimic stroke is vital for emergency department and neurology consultations.
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