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The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy rNAION
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Unilateral acute retinal necrosis in a young Indian male patient

Sachit Mahajan1, Rushil Kumar Saxena1, Manisha Agarwal2

  • 1Department of Vitreo-Retina and Uvea, Dr Shroff's Charity Eye Hospital, New Delhi, New Delhi, India.

BMJ Case Reports
|June 17, 2025
PubMed

Insights

Acute retinal necrosis (ARN), a severe viral eye infection, was diagnosed in a child. Early treatment with antiviral therapy led to positive visual and anatomical outcomes.

Area of Science:

  • Ophthalmology
  • Virology
  • Infectious Diseases

Background:

  • Acute retinal necrosis (ARN) is a rare, rapidly progressive viral retinitis.
  • Herpes simplex virus (HSV) and varicella zoster virus are common causes of ARN.

Purpose of the Study:

  • To report a case of unilateral ARN in a middle childhood patient.
  • To highlight the importance of early diagnosis and management of ARN.

Main Methods:

  • Clinical ocular examination.
  • Polymerase chain reaction (PCR) testing of aqueous humor.
  • Intravitreal and systemic antiviral therapy.

Main Results:

  • Diagnosis of unilateral ARN confirmed by PCR positive for HSV I and II.
  • Successful treatment with antiviral therapy.

Conclusions:

  • Early diagnosis and prompt management are crucial for optimal visual and anatomical outcomes in ARN.
  • HSV I and II can cause ARN in children.
Keywords:
Infectious diseasesPaediatricsRetina

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