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General Strategy to Access N-Aryl Heptamethine Indocyanines for Optical Tuning
1College of Materials, Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province (IKKEM), Xiamen University, Xiamen 361005, China.
None:
We herein report a three-step methodology for the facile construction of N-aryl heptamethine indocyanine (Cy7) dyes. A comparative screening was first conducted to identify the optimal synthetic strategy for N-aryl indoleninium as the key precursor. The subsequent process refinement enabled efficient preparation of N-aryl Cy7 derivatives. Integrated NMR spectroscopy, theoretical calculations, and photophysical characterization revealed how N-arylation modulates the physiochemical properties of the Cy7 scaffold, spanning molecular conformation, electronic configuration, and photophysical characteristics.
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Isomers are different chemical species that have the same chemical formula.
Transition metal complexes often exist as geometric isomers, in which the same atoms are connected through the same types of bonds but with differences in their orientation in space. Coordination complexes with two different ligands in the cis and trans positions from a ligand of interest form isomers. For example, the octahedral [Co(NH3)4Cl2]+ ion has two isomers (Figure 1) In the cis...