Related Experiment Video
Updated: Sep 19, 2025

Use of the EpiAirway Model for Characterizing Long-term Host-pathogen Interactions
Published on: September 2, 2011
Perspective: host factors variants and the underlying causes of long COVID
1Department of Medical Technology, College of Allied Health Sciences, Rattana Bundit University (Pathumthani Campus), Pathumthani, Thailand.
Abstract:
Long COVID, also known as post-COVID syndrome (PCS), is characterized by persistent and unexplained symptoms that can occur not only in individuals who experienced severe symptoms during the acute phase of SARS-CoV-2 infection but also in those who were asymptomatic or had only mild symptoms. These symptoms may persist for months, even in individuals who test negative via nasopharyngeal swab samples. This proposal aims to explain the cause of long COVID through the concept of host factor variants, including cellular variants and major histocompatibility complex (MHC) polymorphisms. A key aspect of this hypothesis is the role of antigen-presenting cells, such as macrophages and dendritic cells. It is proposed that blood or white blood cells could serve as suitable samples for diagnosing long COVID in affected individuals.
More Related Videos
Related Concept Videos
Factors Affecting Illness
For instance, risk factors are connected to illness,...
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
Dimensions of Health and Illness
Chronic Obstructive Pulmonary Disease-I: Introduction
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation

