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Near-Infrared Emission Perovskites for Multifunctional Bioimaging
Tianchi Wang1,2, Jiabo Sun2, Zhaowei Teng1
1The Central Laboratory and Department of Orthopedic The Second Affiliated Hospital of Kunming Medical University Kunming Yunnan 650106 P. R. China.
Small Science
|June 18, 2025
Summary
This study introduces novel Cs2AgInCl6:Yb3+ perovskites for advanced bioimaging. These materials significantly enhance near-infrared emission, enabling superior in vivo tissue visualization with a single detector.
Area of Science:
- Materials Science
- Biomedical Engineering
- Optics
Background:
- Bioimaging is crucial for detecting pathologies noninvasively.
- Current limitations include the need for multiple detectors for comprehensive in vivo data.
- Achieving high resolution and sensitivity simultaneously remains a challenge.
Purpose of the Study:
- To develop a multifunctional bioimaging material using Cs2AgInCl6:Yb3+ perovskites.
- To overcome the limitations of multiple photodetectors in in vivo imaging.
- To enhance near-infrared (NIR) emission for superior tissue presentation.
Main Methods:
- Synthesized Cs2AgInCl6:Yb3+ perovskites with co-incorporated foreign dopants.
- Investigated structural and optical properties, including local symmetry and electron-phonon coupling.
- Evaluated X-ray excited NIR light output and performance in a single InGaAs detector system.
Main Results:
- Co-doping significantly boosted NIR intensity by 40-fold compared to undoped perovskites.
- Achieved X-ray excited NIR light output 2.83 times greater than commercial Bi4Ge3O12 scintillators.
- Demonstrated multifunctional bioimaging with detailed in vivo tissue information using a single detector.
Conclusions:
- The developed Cs2AgInCl6:Yb3+ perovskites offer a promising platform for advanced bioimaging.
- The material's enhanced NIR emission and efficient X-ray to NIR conversion facilitate superior tissue visualization.
- This work provides a viable pathway for promoting bioimaging technologies with integrated tissue presentation.
