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From genomics to precision medicine in type 2 diabetes
Humberto García-Ortiz1, Francisco M Barajas-Olmos1, Cecilia Contreras-Cubas1
1Laboratorio de Inmunogenómica y Enfermedades Metabólicas, Instituto Nacional de Medicina Genómica, Mexico City, Mexico.
Gaceta Medica De Mexico
|June 18, 2025
Summary
Genomic medicine is advancing clinical practice, offering insights into the genetic underpinnings of type 2 diabetes (T2DM). This review explores T2DM genomics in Mexico and its clinical applications.
Area of Science:
- Genomics
- Clinical Practice
- Public Health
Background:
- Type 2 diabetes (T2DM) is a significant public health concern and a leading cause of mortality in Mexico.
- Genomic medicine, driven by technological advancements, is increasingly integrated into clinical practice.
- Despite being nascent, genomic research in Mexico has contributed to understanding T2DM's etiopathogenesis.
Purpose of the Study:
- To review the applications of genomic knowledge in clinical practice.
- To summarize advances in the genomics of T2DM specifically within the Mexican context.
Main Methods:
- Literature review of genomic studies related to T2DM.
- Analysis of genomic medicine implementation in clinical settings.
- Synthesis of current knowledge on T2DM genetics in Mexico.
Main Results:
- Genomic studies are beginning to elucidate the genetic factors contributing to T2DM in Mexico.
- Innovative technologies facilitate the identification of genetic predispositions to diseases like T2DM.
- Genomic medicine offers potential for personalized risk assessment and treatment strategies.
Conclusions:
- Genomic insights are crucial for understanding and managing T2DM.
- Further development of genomic studies in Mexico is essential for public health.
- Integrating genomic medicine into clinical practice holds promise for addressing T2DM prevalence.
Keywords:
Diabetes tipo 2FarmacogenómicaGenomic medicineMedicina de precisiónMedicina genómicaPharmacogenomicsPolygenic risk scoresPrecision medicinePuntajes de riesgo poligénicoType 2 diabetesMore Related Videos
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