Overweight and obesity in pregnancy - a retrospective cohort study in Germany
Clara Illi1, Lars Hellmeyer2, Elena Groening3
1Obstetrics, Charité University Hospital Berlin, Berlin, Germany.
Abstract:
Overweight and obesity are common among women of reproductive age. 43.8% of women in Germany and 50% of women in the US entering their pregnancy have a body mass index (BMI)≥25. Studies indicate that gestational overweight is associated with maternal and neonatal complications.2034 women from 2015 until 2018 were included. Trends in BMI, gestational weight gain, pregnancy outcome, complications, neonatal weight, and outcome were analyzed. Gestational weight gain was evaluated according to the Institute of Medicine (IOM) guidelines. 34% of the population were overweight with a BMI≥25. The overall weight gain was similar across BMI groups (median 11.0-14.0 kg). 44.1% gained more than recommended. These women were at higher risk of labor induction (33.1% vs. 27.0%, p=0.003), unplanned cesarean section (18.6% vs. 13.6%, p=0.004), lower incidence of spontaneous vaginal birth (54.5% vs. 59.9%, p=0.009), and higher neonatal birth weight (>90th percentile, 14.5% vs. 5.7%, p<0.001). Gestational diabetes was linked to a lower gestational weight gain (odds ratio 0.92, confidence interval 0.90-0.95, p<0.001).One third of the analyzed population was already overweight or obese at the beginning of the pregnancy. In 44.1% of cases, weight gain during pregnancy exceeded the recommended amount. This was associated with complications in pregnancy and labor as well as higher neonatal birth weight. This study highlights the importance of prenatal counseling and intervention on BMI and weight gain.
More Related Videos
14:56Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies
Published on: May 6, 2022
08:30Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes
Published on: March 15, 2018
Related Concept Videos
Obesity
Diabetes Mellitus: Type 2 and Gestational
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Bias in Epidemiological Studies
Regression Toward the Mean
Study Designs in Epidemiology
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
