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Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

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Minimally Invasive Glaucoma Surgery: Is It Here to Stay?

Neeranjali Jain¹, Jennifer C Fan Gaskin^1,2,3

¹Glaucoma Research and Investigation Unit, Royal Victorian Eye and Ear Hospital, East Melbourne, Victoria, Australia.

Clinical & Experimental Ophthalmology

|June 19, 2025

Summary

Minimally invasive glaucoma surgery (MIGS) offers safer options for lowering eye pressure. This review covers MIGS categories, efficacies, and their role in evolving glaucoma treatment.

Keywords:

MIGS glaucoma surgery

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Area of Science:

Ophthalmology
Surgical Innovation

Background:

Glaucoma treatment traditionally involves incisional surgeries with significant complication risks.
Minimally invasive glaucoma surgery (MIGS) has emerged as a safer alternative for intraocular pressure (IOP) reduction.

Purpose of the Study:

To review the categories and mechanisms of MIGS procedures.
To analyze the efficacy, safety, advantages, and limitations of various MIGS devices.
To explore the future impact of MIGS on the glaucoma treatment paradigm.

Main Methods:

Review of current literature on MIGS devices and their surgical techniques.
Analysis of published safety and efficacy data for different MIGS categories.
Comparative assessment of MIGS versus traditional glaucoma surgeries.

Main Results:

MIGS enhance aqueous outflow via trabecular or suprachoroidal/subconjunctival pathways.
MIGS generally offer a favorable safety profile compared to incisional glaucoma surgery.
A growing range of MIGS options allows for tailored treatment based on patient-specific IOP targets and glaucoma etiology.

Conclusions:

MIGS represent a significant advancement in glaucoma management, expanding treatment choices.
The continued development and adoption of MIGS are likely to reshape the future of glaucoma surgical care.
Personalized glaucoma treatment is enhanced by the availability of diverse MIGS procedures.