Related Experiment Video
Updated: Sep 19, 2025

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
Published on: June 4, 2017
Association between climate indicators and hay fever incidence in children and adolescents in Freiburg, Germany
Trang Dao-Siebel1,2, Jakob Holstiege3, Kathrin Graw4
1Faculty of Economics and Behavioral Sciences, University of Freiburg, Freiburg, Germany.
Background:
Allergic conditions including hay fever are a sentinel measure of environmental impact on human health in early life. In this study we investigated the association between climate indicators and allergic rhinitis (hay fever) incidence in children and adolescents in Freiburg im Breisgau (Germany), as a representative study site for an urban German environment.
Methods:
Data on climate indicators and hay fever incidence in children and adolescents in the period 2013 to 2021 were implemented within the free software environment for statistical computing R using generalized additive Gamma family models.
Results:
Our results from all "seasonal", "non-seasonal", and "single-factor" models could not support the associations between the hay fever incidence and the precipitation as well as the concentrations of PM10, NO2, and O3 in Freiburg. However, they indicated statistically significant associations with temperature, and wind speed at the 5% level. The hay fever incidence was highest, as the temperature was between 4-6°C, and 10-17°C, and the wind speed was between 2.0 and 2.1m/s.
Conclusions:
This knowledge could be of relevance for the choice of patient treatment procedure in Freiburg, as the symptoms of a cold or flu can easily be mistaken for an allergy, especially in the cold season.
Related Concept Videos
Asthma-I: Introduction
Asthma-III: Symptoms and Complications
Classification of Asthma
Allergic Reactions
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:

