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Effect of Creatine Supplementation on Body Composition in Cancer Patients: A Systematic Review
Asier Del Arco1, Saioa Aguirre-Elordui1, Jurgi Olasagasti-Ibargoien1
1Health, Physical Activity and Sports Science Laboratory, Department of Physical Activity and Sports, University of Deusto, Bilbao, Spain.
Nutrition and Cancer
|June 19, 2025
Summary
Creatine supplementation (CrS) shows limited significant effects on body composition in cancer patients. While generally safe, its benefits for cancer patients require further research, especially with less aggressive treatments.
Area of Science:
- Nutrition Science
- Oncology
- Sports Medicine
Background:
- Creatine is a naturally occurring compound vital for muscle energy.
- Diet and supplementation are sources of creatine.
- Emerging research suggests potential therapeutic roles in chronic diseases.
Conclusions:
- Evidence for significant body composition improvements from creatine supplementation in cancer patients is currently limited.
- Creatine supplementation appears safe for cancer patients.
- Potential benefits may be more pronounced in patients undergoing less aggressive treatments or those with non-metastatic disease.
- Further research is necessary to establish creatine's role in cancer care and body composition management.
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