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Updated: Sep 18, 2025

Intracavernosal Pressure Recording to Evaluate Erectile Function in Rodents
Published on: June 6, 2018
Prevalence of cardiac dysfunction in men with erectile dysfunction: the EDcard study
Emil Durukan1,2,3, Christian Fuglesang S Jensen1, Maria Dons2,4
1Department of Urology, Copenhagen University Hospital - Herlev and Gentofte, Herlev, Denmark.
Objectives:
To assess the prevalence of myocardial impairment in men with erectile dysfunction (ED) as compared with the general population using conventional and two-dimensional speckle-tracking echocardiography.
Subjects And Methods:
In this cross-sectional study, men with ED underwent clinical, electrocardiographic, and transthoracic echocardiographic evaluation including left ventricular ejection fraction (LVEF) and global longitudinal strain (GLS) according to a predefined protocol. All participants were matched 1:1 with controls from the general population on sex, age, and body mass index (BMI).
Results:
In total, 796 people were included, 398 men with ED and 398 controls. The ED group had a median (interquartile range [IQR]) age of 61 (53-70) years and a median (IQR) BMI of 26.3 (24-29) kg/m2. Left ventricular (LV) systolic dysfunction was found in 232 (58.3%) men with ED compared to 102 (25.6%) controls (P < 0.001). Nineteen (4.8%) men with ED were referred for further cardiovascular evaluation.
Conclusion:
More than half of men with ED exhibited signs of cardiac dysfunction, particularly LV systolic dysfunction. Further research should explore the long-term prognostic implications of these findings.
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