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Intra-nasal Disodium Orthophosphate Is Beneficial in Improving Olfactory Dysfunction Post COVID-19

Mohamed S Imam1, Manal A A Alghamdi2, Jasmine N A Albukhari3

  • 1Department of Clinical Pharmacy, National Cancer Institute, Cairo University, Cairo, Egypt.

The Annals of Otology, Rhinology, and Laryngology
|June 20, 2025
PubMed
Summary

Intranasal disodium orthophosphate significantly reduced nasal calcium levels in COVID-19 patients with persistent olfactory dysfunction. This treatment improved smell function in 81% of participants, offering a potential therapy for post-COVID-19 smell loss.

Keywords:
COVID-19calciumchelating agentdisodium orthophosphateolfactory dysfunction

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