Repair of a Nasal Tip Defect Using Graft and Patch Versions of a Deep-Frozen Amniotic Membrane: A Case Report

This report describes the clinical course of a patient who underwent radical excision of a basal cell carcinoma and subsequent reconstruction using a Zitelli modification of the bilobed flap, which resulted in a nasal tip defect. The patient did not wish to undergo another surgical nose reconstruction; thus, the author used a two-stage application method with deep-frozen amniotic membrane to treat the nasal tip defect. The first application-the graft version-was applied to exposed cartilaginous structures, initiating tissue restoration. Seven days later, the author observed complete absorption of the amniotic membrane, wound bed granulation with overlapping cartilaginous structures, and peripheral epithelialization. The second application-the patch version-supported tissue restoration and acted as a biological cover. This method provides a better aesthetic outcome and shorter healing time compared with secondary intention wound healing. It may be indicated for patients with skin defects on the nasal tip who do not want to or who cannot undergo surgical intervention.