Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nitrous oxide ameliorates spasmodic torticollis.

M A Gillman, R Sandyk

    European Neurology
    |January 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Nitrous oxide (N2O) temporarily improved symptoms in a patient with therapy-resistant spasmodic torticollis. This suggests the opioid system could be a target for treating this condition.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Tobacco cessation and new indications for N2O/O2 sedation.

    SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging·2008
    Same author

    Psychotropic analgesic nitrous oxide for alcoholic withdrawal states.

    The Cochrane database of systematic reviews·2007
    Same author

    Most effective method in routine conscious sedation for ambulatory patients.

    SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging·2004
    Same author

    Overcautiousness can be a disservice.

    SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging·2002
    Same author

    Possible role of the endogenous opioid system in the placebo response in depression.

    The international journal of neuropsychopharmacology·2002
    Same author

    Psychotropic analgesic nitrous oxide (PAN) for hyperactivity.

    The Australian and New Zealand journal of psychiatry·2001

    Area of Science:

    • Neurology
    • Pharmacology

    Background:

    • Spasmodic torticollis is a debilitating movement disorder characterized by involuntary neck muscle contractions.
    • Therapy-resistant cases present significant challenges in management.

    Observation:

    • A patient with therapy-resistant spasmodic torticollis was administered nitrous oxide (N2O).
    • The administration of N2O led to a significant, albeit temporary, reduction in dystonic movements.

    Findings:

    • Nitrous oxide (N2O) demonstrated a marked, transient amelioration of spasmodic torticollis symptoms.
    • This observation points towards a potential role for the opioid system in the condition's pathology and treatment.

    Implications:

    • Modulating the opioid system may offer a novel therapeutic strategy for spasmodic torticollis.

    Related Experiment Videos

  • Further research into N2O's mechanism could elucidate the underlying pathogenesis of this movement disorder.