In vivo Testing of the Pressio Intracranial Pressure Monitor

Area of Science:

• Neurosurgery
• Critical Care Medicine
• Biomedical Engineering

Background:

• Accurate intracranial pressure (ICP) monitoring is vital for managing acute brain injuries.
• The Pressio intraparenchymal strain gauge transducer is a device used for ICP measurement.

Purpose of the Study:

• To evaluate the zero drift of the Pressio intraparenchymal strain gauge transducer under clinical conditions.
• To assess the reliability and precision of the Pressio transducer for long-term ICP monitoring.

Main Methods:

• A prospective, observational, multicenter study was conducted in four French intensive care units.
• 235 patients with acute brain injuries requiring ICP measurement with the Pressio transducer were included.
• Zero drift was measured at sensor explantation, and ICP-related adverse events were collected.

Main Results:

• The median zero drift was 1 mm Hg (IQR 1-3 mm Hg) over a median monitoring period of 8 days (2,180 total monitoring days).
• A weak, clinically insignificant correlation was found between monitoring duration and zero drift (ρ=0.141, P=0.0357).
• 10% of transducers showed zero drift >5 mm Hg; 1.8% had ICP-related hematomas with no clinical impact; 2.6% experienced monitoring failures.

Conclusions:

• The Pressio transducer demonstrates minor zero drift, comparable to other strain gauge ICP devices.
• The device is precise and reliable for clinical intracranial pressure monitoring in patients with acute brain injuries.