Related Experiment Video
Updated: Sep 18, 2025

Synthesis of a Thiol Building Block for the Crystallization of a Semiconducting Gyroidal Metal-sulfur Framework
Published on: April 9, 2018
Harnessing Radicals for the Selenotrifluoromethylation within a Confined Metal-Organic Framework
Cong Zhao1, Xianzhi Lan1, Jiabin Chen1
1School of Environmental and Chemical Engineering, Wuyi University, Jiangmen 529020, China.
Abstract:
Herein, we report a UiO-67-type metal-organic framework as an efficient photocatalyst for the selenyltrifluoromethylation of terminal alkynes. The CF3• radical species can be effectively stabilized within the confined space of UiO-67-Ru, which contributes to the superior regio-selectivity and catalytic activity. Furthermore, the stereo-selectivity of the obtained (E)-α,β-unsaturated selenotrifluoromethyl compounds is well elucidated by means of density functional theory (DFT) calculations and canonical Monte Carlo (CMC) simulation.
More Related Videos
Related Concept Videos
Preparation and Reactions of Sulfides
Radical Substitution: Allylic Bromination
Radicals: Electronic Structure and Geometry
Accordingly, the structure of a trivalent radical lies between the geometries of carbocations and carbanions. An sp2-hybridized carbocation is trigonal planar, while an sp3-hybridized carbanion is trigonal pyramidal. Here, the difference in geometry is...
Radical Halogenation: Stereochemistry
Halogenation to form a new chiral center:
Radical Substitution: Hydrogenolysis of Alkyl Halides with Tributyltin Hydride
The bonds formed in this reaction are stronger than the bonds broken, making it energetically favorable. The reaction follows a radical chain mechanism similar to radical halogenation...
Radical Reactivity: Nucleophilic Radicals

