Mapping current research status and emerging frontiers of lipidomics: a comprehensive data-mining-based study.

Area of Science:

• Lipidomics research spans multiple scientific disciplines, including molecular biology, genetics, clinical medicine, and materials science.

Background:

• Lipids are vital biomolecules, and altered lipid profiles are linked to numerous disorders.
• Lipidomics advances have improved understanding of lipid metabolism, but research gaps persist.

Purpose of the Study:

• To conduct a comprehensive bibliometric analysis of lipidomics research.
• To identify current research status, key contributors, and emerging frontiers in lipidomics.

Main Methods:

• Collected 7989 publications from the Web of Science Core Collection.
• Utilized bibliometric visualization tools (VOSviewer, CiteSpace) and methods like co-authorship, co-occurrence, co-citation, cluster analysis, and burst detection.

Main Results:

• Publication output in lipidomics shows a consistent increasing trend over 20 years.
• The United States and China lead in publications and funding; University of California System and Prof. Han Xianlin are top contributors.
• Obesity, Alzheimer's disease, and NAFLD are prominent research areas, with keywords highlighting omics approaches, biomarkers, and analytical techniques.

Conclusions:

• This bibliometric analysis offers a novel overview of lipidomics knowledge structure and research trends.
• It provides valuable insights into the field's evolution and future research directions.