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Updated: Sep 18, 2025
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A Brief Review on Transdermal Patches
Shubham Singh1, Dharmendra Singh Rajput2, Naveen Gupta2
1School of Pharmacy, Rai University, Ahmedabad, Gujarat, India.
Summary
Transdermal drug delivery systems offer controlled medication release through skin patches, overcoming oral route challenges. However, skin
Area of Science:
- Pharmaceutical Sciences
- Biomedical Engineering
Background:
- Transdermal drug delivery systems (TDDS) offer an alternative to traditional oral administration.
- TDDS utilize medicated adhesive patches for controlled medication release directly into the bloodstream via the skin.
Purpose of the Study:
- To provide a comprehensive review of transdermal patches.
- To discuss the types, preparation methods, and influencing factors of transdermal patches.
Main Methods:
- Literature review of transdermal drug delivery systems.
- Analysis of advantages and disadvantages of transdermal patches.
- Overview of transdermal patch preparation and influencing factors.
Main Results:
- Transdermal patches provide controlled drug release, enhancing therapeutic efficacy.
- The skin's barrier function limits TDDS to small-molecule drugs.
- Various types and preparation methods exist for transdermal patches.
Conclusions:
- Transdermal drug delivery presents a viable alternative for specific medications.
- Understanding preparation methods and influencing factors is crucial for effective TDDS design.
- Further research may overcome skin barrier limitations for larger molecules.
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