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Updated: Sep 18, 2025

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis
Published on: March 4, 2014
[Neuralgic amyotrophy]
Kristoffer N Skaastrup1, Carolina C Graffe2, Siska Frahm-Falkenberg2
1Neurologisk Afdeling, Kæbenhavns Universitetshospital - Nordsjællands Hospital.
Abstract:
This review provides an overview of neuralgic amyotrophy (NA) to improve treatment and collaboration. The disorder is a neuropathy characterized by acute onset of asymmetric severe pain, paresis, atrophy, and sensory deficits followed by prolonged remission. The incidence of NA is likely higher than previously assumed. Initial treatment includes a combination of long-lasting NSAIDs and slow-release opioids, while corticosteroids may be considered in severe cases. Physical therapy is reserved for chronic phase treatment. Electrophysiological tests and ultrasound may aid the clinical diagnosis.
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