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Updated: Sep 18, 2025

Prion Safety Laboratory Swipe Test
Published on: February 14, 2025
[Prion diseases]
1Cellule nationale de référence des maladies de Creutzfeldt-Jakob, hôpital de la Pitié-Salpêtrière, AP-HP, Paris.
Abstract:
PRION DISEASES. Prion diseases or subacute transmissible spongiform encephalopathies (TSE) are neurodegenerative diseases. The agent responsible for the disease and its transmission is a protein with an abnormal conformation, derived from a normal protein: the PrP protein. TSE exist in several forms: sporadic Creutzfeldt-Jakob disease (CJD) (the most common), genetic and iatrogenic forms. Variant CJD is the only form linked to bovine spongiform encephalopathy. Despite therapeutic trials carried out since the early 2000s, no treatment has yet demonstrated its effectiveness.
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