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Updated: Sep 18, 2025

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Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
Published on: November 12, 2015
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Advances in IOL calculations in patients with keratoconus.
Assaf Gershoni1,2,3, Graham D Barrett2,3, Ruti Sella4
1Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Therapeutic Advances in Ophthalmology
|June 23, 2025
Summary
New intraocular lens (IOL) formulas improve cataract surgery outcomes for keratoconus patients. These specialized formulas, like Barrett True-K and Kane Keratoconus, reduce refractive prediction errors in eyes with this progressive corneal disease.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Refractive Surgery
Background:
- Keratoconus causes corneal thinning and irregular astigmatism, complicating cataract surgery.
- Traditional intraocular lens (IOL) calculation formulas often result in significant refractive errors in keratoconus eyes.
- This leads to hyperopic shifts and reduced patient satisfaction after cataract surgery.
Purpose of the Study:
- To review the impact of keratoconus on IOL calculations.
- To highlight advanced IOL formulas designed for keratoconus.
- To provide clinical recommendations for improved surgical outcomes.
Main Methods:
- Literature review of current studies on IOL calculations in keratoconus.
- Assessment of specialized formulas such as Barrett True-K and Kane Keratoconus.
- Analysis of formula effectiveness and clinical outcomes.
Main Results:
- Traditional formulas yield inaccurate IOL power in keratoconus patients.
- Specialized formulas demonstrate improved refractive predictability.
- Barrett True-K and Kane Keratoconus formulas show promise in managing keratoconus eyes.
Conclusions:
- Keratoconus significantly impacts IOL calculation accuracy.
- Advanced formulas like Barrett True-K and Kane Keratoconus offer better refractive outcomes.
- Clinical adoption of these specialized formulas is recommended for keratoconus patients.
Keywords:
Barrett True-KIOL calculation formulasKane keratoconuscataract surgeryclinical recommendationscorneal irregularitiesintraocular lens (IOL) calculationkeratoconusposterior corneal astigmatismrefractive prediction errorsurgical outcomesMore Related Videos
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