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The effect of Artificial Intelligence Health Education Accurately Linking System on childhood asthma: study protocol

Huan-Fang Wang¹, Yun-Hua Li², Qiaoling Zhang³

¹Nursing Department, Inner Mongolia Maternal and Child Health Care Hospital, Hohhot, China.

Frontiers in Psychiatry

|June 23, 2025

Insights

This pilot study explores AI-driven interventions for childhood asthma self-management. The AI Health Education Accurately Linkage System (AI-HEALS) aims to improve symptom control and reduce healthcare costs for families with asthmatic children.

Area of Science:

Pediatric Pulmonology
Digital Health
Artificial Intelligence in Medicine

Background:

Childhood asthma is a widespread chronic condition requiring significant self-management by children and parents.
Traditional face-to-face education often falls short in providing personalized, ongoing support for asthma self-management.
Advancements in artificial intelligence (AI) offer new opportunities to enhance self-management strategies for pediatric asthma.

Purpose of the Study:

To evaluate the efficacy of an AI-driven intervention, AI Health Education Accurately Linkage System (AI-HEALS), in improving self-management capabilities for families with asthmatic children.
To determine if AI-HEALS can lead to better asthma symptom control and reduced medical costs.
To assess the impact of AI-HEALS on various physiological indicators, parental self-management behaviors, and mental health.

Main Methods:

A pilot single-blind randomized controlled trial (RCT) will be conducted.
Participants will be families with children diagnosed with asthma, randomly assigned to an intervention or control group.
The intervention group will receive standard care plus AI-HEALS delivered via WeChat, featuring an AI chatbot, physiological monitoring, reminders, and tailored educational content.

Main Results:

The primary outcome is the change in asthma symptom control levels.
Secondary outcomes include physiological indicators, parental self-management behaviors, and mental health.
AI-HEALS utilizes a knowledge base aligned with pediatric asthma guidelines for accuracy.

Conclusions:

This study investigates the potential of integrating AI and mobile health (mHealth) to support childhood asthma self-management.
The AI-HEALS system aims to empower families to better manage their child's asthma.
The findings will provide insights into the effectiveness of AI-driven interventions for pediatric asthma control.

Read full analysis

Abstract

Background:

Childhood asthma is a prevalent chronic disease that affects millions of children worldwide. Managing this disease demands not only medical treatment but also the long-term self-management efforts of both children and their parents. Conventional self-management education typically depends on face-to-face approaches, often failing to take into account the personalized requirements and ongoing support needed. Nevertheless, with the evolution of artificial intelligence (AI) technology, fresh prospects have emerged to boost the effectiveness of self-management for childhood asthma. Based on it, we have designed an AI Health Education Accurately Linkage System (AI-HEALS) to explore whether AI-driven interventions can improve self-management capabilities of families with asthmatic children, thereby helping them control the disease and reduce medical costs.

Methods:

This research is a pilot single-blind randomized controlled trial (RCT) intended to gauge the efficacy of the AI-HEALS intervention delivered via the WeChat platform in enhancing the self-management abilities of families with asthmatic children. Participants will be recruited from eligible families whose children have been diagnosed with asthma and randomly allocated to either the intervention group or the control group. The control group will receive standard treatment, whereas the intervention group will receive both standard treatment and the AI-HEALS intervention. The intervention includes an AI-enabled, voice-activated interactive question-and-answer system, as well as monitoring and recording of physiological indicators, regular reminders, and customized educational articles. All components of the intervention will mainly be provided through a WeChat official account named "Children's Asthma Health Management Expert." AI-HEALS will construct its knowledge base according to pediatric asthma treatment guidelines to enhance the accuracy and reliability of the information it offers. The primary outcome measure is the alteration in asthma symptom control levels, while secondary outcomes comprise a variety of other physiological indicators related to asthma, parents' self-management behaviors, and mental health conditions.

Discussion:

This study combines AI and mobile health technology to develop the AI-HEALS system, with the aim of assisting families of children with asthma in controlling the disease symptoms. The primary objective is to evaluate whether the intervention can improve asthma symptom control.

Clinical Trial Registration:

The study is scheduled to begin in April 2025 and is expected to conclude in December 2026. This research protocol is the first version and was registered with the China Clinical Trial Registration Center on February 14, 2025 (Registration Number: ChiCTR2500097233).

Keywords:

RCT artificial intelligence childhood asthma chronic disease large language model mobile health

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