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Peripherex Home Visual Field Demonstrates High Test-Retest Reliability, Validity
Justin Schweitzer1, Mitch Ibach1, John Berdahl1
1Vance Thompson Vision, Sioux Falls, SD, USA.
Clinical Ophthalmology (Auckland, N.Z.)
|June 23, 2025
Summary
Home-based visual field testing using the Peripherex Visual Field Test (PRX-VFT) app is feasible and correlates well with in-office Humphrey Field Analyzer (HFA) testing for glaucoma patients.
Area of Science:
- Ophthalmology
- Medical Technology
Background:
- Glaucoma care faces unmet needs in disease assessment and progression monitoring.
- Current visual field testing methods have limitations in accessibility and frequency.
Purpose of the Study:
- To evaluate a novel home-based app, Peripherex Visual Field Test (PRX-VFT), for visual field testing.
- To compare the PRX-VFT's performance against in-office Humphrey Field Analyzer (HFA) data.
Main Methods:
- An observational, multicenter, open-label clinical trial was conducted.
- Patients with glaucoma, glaucoma suspect, or ocular hypertension were enrolled.
- PRX-VFT tests were performed and compared to matched HFA data.
Main Results:
- Test-retest reliability for PRX-VFT was good (ICC 0.7596).
- PRX-VFT demonstrated excellent sensitivity (95.7%) and NPV (98.27%) for detecting abnormal fields.
- PRX-VFT showed very good specificity (79.26%) and PPV (66.36%) for detecting normal fields.
- Patients found PRX-VFT easier and more enjoyable than HFA.
Conclusions:
- Home-based visual field testing with PRX-VFT is feasible and statistically correlates with in-office HFA testing.
- PRX-VFT offers a potential method to enhance glaucoma patient care with minimal additional cost.
