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Management of Opioid Use Disorder Among Peripartum Individuals During Hospitalization
Journal of Addiction Medicine
|June 23, 2025
Summary
Hospitalization offers a key chance to start medication for opioid use disorder (MOUD) for peripartum individuals. Understanding why many leave treatment early is crucial for better care.
Area of Science:
- Obstetrics and Gynecology
- Addiction Medicine
- Public Health
Background:
- Peripartum opioid use disorder (OUD) presents significant public health challenges.
- Limited understanding exists regarding the inpatient management of pregnant and postpartum individuals with OUD.
Purpose of the Study:
- To characterize hospitalized peripartum individuals with OUD who received a consultation.
- To examine the inpatient treatment of OUD in this population.
Main Methods:
- Retrospective cohort study of peripartum individuals receiving OUD consults (May 2020-April 2022).
- Data collected included substance use, psychosocial history, medication for opioid use disorder (MOUD) initiation and acceptance, and discharge plans.
Main Results:
- 63% of individuals not on MOUD at admission initiated treatment during hospitalization, commonly buprenorphine-naloxone.
- 74% were linked to outpatient OUD treatment at discharge.
- 35% self-directed their discharge, with higher rates among those not receiving inpatient MOUD (P < 0.01).
Conclusions:
- Hospitalization is a critical opportunity for initiating MOUD and connecting peripartum individuals to ongoing community OUD services.
- Further research is needed to understand factors driving high rates of self-directed discharge in this population.
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