Related Experiment Video

Updated: Sep 18, 2025

Author Spotlight: A Pharmacodissection Approach to Uncover Mechanisms in Cardiovascular Disease Risk Populations
08:21

Author Spotlight: A Pharmacodissection Approach to Uncover Mechanisms in Cardiovascular Disease Risk Populations

Published on: July 21, 2023

1.5K

Exercise-Induced SOD3/H2O2 Sulfenylates PKG1α to Restore Vasodilation in Diabetes

Varadarajan Sudhahar1,2,3, Kareem Abdelsaid1,4, Philip Eaton5

  • 1Vascular Biology Center (V.S., K.A., S.K., M.U.-F., T.F.), Medical College of Georgia at Augusta University.

Circulation Research
|June 24, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
cyclic GMP-dependent protein kinasediabetes mellitusexercisehydrogen peroxidesuperoxide dismutasesuperoxidesvasodilation

More Related Videos

Combined Intravital Microscopy and Contrast-enhanced Ultrasonography of the Mouse Hindlimb to Study Insulin-induced Vasodilation and Muscle Perfusion
08:22

Combined Intravital Microscopy and Contrast-enhanced Ultrasonography of the Mouse Hindlimb to Study Insulin-induced Vasodilation and Muscle Perfusion

Published on: March 20, 2017

8.8K
Method of Direct Segmental Intra-hepatic Delivery Using a Rat Liver Hilar Clamp Model
09:22

Method of Direct Segmental Intra-hepatic Delivery Using a Rat Liver Hilar Clamp Model

Published on: April 2, 2017

14.2K

Related Experiment Videos

Last Updated: Sep 18, 2025

Author Spotlight: A Pharmacodissection Approach to Uncover Mechanisms in Cardiovascular Disease Risk Populations
08:21

Author Spotlight: A Pharmacodissection Approach to Uncover Mechanisms in Cardiovascular Disease Risk Populations

Published on: July 21, 2023

1.5K
Combined Intravital Microscopy and Contrast-enhanced Ultrasonography of the Mouse Hindlimb to Study Insulin-induced Vasodilation and Muscle Perfusion
08:22

Combined Intravital Microscopy and Contrast-enhanced Ultrasonography of the Mouse Hindlimb to Study Insulin-induced Vasodilation and Muscle Perfusion

Published on: March 20, 2017

8.8K
Method of Direct Segmental Intra-hepatic Delivery Using a Rat Liver Hilar Clamp Model
09:22

Method of Direct Segmental Intra-hepatic Delivery Using a Rat Liver Hilar Clamp Model

Published on: April 2, 2017

14.2K

Related Concept Videos

Antihypertensive Drugs: Vasodilators01:23

Antihypertensive Drugs: Vasodilators

659
Vasodilators, primarily affecting the smooth muscles within arterial and venous walls, are commonly used for hypertension treatment. Medications such as minoxidil and hydralazine primarily target arteries and arterioles, while sodium nitroprusside acts on arterioles and venules. Minoxidil, functioning as a prodrug, is metabolized by hepatic sulfotransferase into its active form, minoxidil sulfate, after oral administration. This metabolite binds to the sulfonylurea receptor (SUR) component of...
659

Articles linked to this work by shared authors, journal, and citation graph.

Myeloid DRP1 Sulfenylation Drives Reparative Macrophage Polarization and Neovascularization in Ischemic Muscle.

Antioxidants (Basel, Switzerland)·2026

Endothelial Drp1 integrates VEGF-induced redox signaling with glycolysis through cysteine oxidation to drive angiogenesis.

Nature communications·2026

Purine metabolic adaptation protects the endothelium from disturbed flow-induced DNA damage and atherosclerosis.

Proceedings of the National Academy of Sciences of the United States of America·2026

Nox1-Derived ROS Amplifies Calcium Entry and Enhances Pneumolysin-Induced Lung Endothelial Barrier Dysfunction in Hyperglycemia.

Antioxidants (Basel, Switzerland)·2026

Myeloid DRP1 Sulfenylation Drives Reparative Macrophage Polarization and Neovascularization in Ischemic Muscle.

bioRxiv : the preprint server for biology·2026

SHP2: A Redox-Sensitive Regulator Linking Immune Checkpoint Inhibitor Therapy to Cancer Treatment and Vascular Risk.

Antioxidants (Basel, Switzerland)·2025

Gut Dysbiosis Promotes Myocardial Hypertrophy via GBP2b/GBP1 in Chronic Colitis.

Circulation research·2026

Blood Metabolomic Signatures of 1-Hour Glucose Predict Cardiometabolic Risk.

Circulation research·2026

Hepatic ChREBP Drives Cardiac Remodeling via ApoM Nontranscriptional Repression.

Circulation research·2026

Mitophagy Facilitates Cytosolic Proteostasis to Preserve Cardiac Function.

Circulation research·2026

Regulated HSPG Signaling Directs Epicardial Behavior to Support Cardiac Formation.

Circulation research·2026

FPR1-Driven Neutrophil-Endothelial Cell Axis Promotes Angiogenesis in PAOD.

Circulation research·2026

Sun exposure and photoprotection: Habits, knowledge, and attitudes among elite beach soccer players.

Photochemistry and photobiology·2026

Characteristics of post-exercise responders versus non-responders following aerobic or isometric exercise in physically inactive adults of African and South Asian Descent with high-normal blood pressure or grade I hypertension.

Blood pressure·2026

Calf and mid-upper arm circumference as screening tools for sarcopenia in elderly diabetics: evidence from primary healthcare centers.

Folia medica·2026

'It helps me stay on track': patient experiences using a mobile app for self-management of systemic sclerosis with a focus on fatigue in women.

Rheumatology advances in practice·2026

Underfueled and overloaded: association between low energy availability symptoms and current self-reported injury status in climbers.

Frontiers in sports and active living·2026

Effects of exercise interventions on sleep quality in breast cancer survivors: a systematic review and meta-analysis.

Frontiers in oncology·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us