[Hemodynamically relevant cardiac relapse of diffuse large B-cell lymphoma]

A 55-year-old female patient presented with a 1-week history of cough, dyspnea, pre-syncopal sensation and a history of asthma and long-lasting complete remission of diffuse large B‑cell lymphoma (LBCL). Imaging revealed a mass measuring 8 × 6.4 × 6.2 cm in the right ventricle and atrium, partially obstructing the cardiac valve plane. Biopsy was performed. With the onset of hemodynamic instability, ex juvantibus antineoplastic therapy was administered. After 36 h, echocardiography already showed a considerable size reduction to approximately 5 × 5 cm. Histology was consistent with relapsed LBCL. Staging showed no further manifestations and salvage therapy was initiated.