Clinical Results of Double-Layer MicroNet Stents in Complex Anatomy

Area of Science:

• Vascular Surgery
• Interventional Cardiology
• Medical Device Technology

Background:

• Carotid Artery Stenting (CAS) is a crucial procedure for stroke prevention.
• Evaluating novel stent designs like the C-Guard is essential for improving patient outcomes.
• Complex vascular anatomies present unique challenges in CAS procedures.

Purpose of the Study:

• To assess the clinical and technical outcomes of Carotid Artery Stenting (CAS) using the C-Guard double-layer stent.
• To compare outcomes in patients with complex versus standard vascular anatomies.
• To evaluate technical success, major adverse events (MAEs), and restenosis rates associated with the C-Guard stent.

Main Methods:

• Retrospective review of 167 patients undergoing CAS between 2019 and 2024.
• Classification of patients into standard and complex anatomy groups based on an anatomical risk score.
• Analysis of technical success, MAEs (death, stroke, myocardial infarction), and restenosis rates.

Main Results:

• High technical success rate of 99.4% for CAS with the C-Guard stent.
• No significant difference in MAEs between standard and complex anatomy groups (P > 0.05).
• Major strokes (4%) and restenosis (4%) were observed exclusively in the complex anatomy group.

Conclusions:

• The C-Guard stent is safe and effective for CAS, even in complex vascular anatomies.
• Comparable outcomes across standard and complex groups suggest broad applicability.
• Further research is needed to optimize patient selection for challenging cases.