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Updated: Sep 18, 2025

Imaging Centrosomes in Fly Testes
Published on: September 20, 2013
Inactivation and Elimination of Centrioles During Development in the Genus Drosophila: Current Insights and Open
Denise Bonente1, Giuliano Callaini1, Maria Giovanna Riparbelli1
1Department of Life Sciences, University of Siena, Via A. Moro 2, 53100 Siena, Italy.
Abstract:
Centrioles are remarkably stable organelles that play a main role in the assembly of centrosomes and ciliary structures. However, there are several differentiated tissues that must eliminate their centrioles to avoid centrosome formation and improper cell proliferation. Therefore, centriole elimination represents an important process in many organisms to ensure successful cell differentiation and maintenance of tissue homeostasis. In this review, we analyzed centriole inactivation and elimination in various Drosophila cell types in relation to the dynamics of the pericentriolar material.
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