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Temporal bone histiocytosis in children: a systematic review
Francesca Galluzzi1, Werner Garavello2
1Department of Otorhinolaryngology, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.
International Journal of Pediatric Otorhinolaryngology
|June 25, 2025
Summary
Temporal bone histiocytosis (TBH) in children presents with ear symptoms and osteolytic lesions. Management requires a multidisciplinary approach with long-term follow-up for potential recurrences and complications.
Area of Science:
- Pediatric Otolaryngology
- Pediatric Radiology
- Pediatric Endocrinology
Background:
- Temporal bone histiocytosis (TBH) is a rare condition affecting children.
- Early diagnosis and treatment are crucial for managing this condition.
Purpose of the Study:
- To analyze the diagnosis, treatment, and outcomes of temporal bone histiocytosis (TBH) in children.
- To highlight the importance of a multidisciplinary approach and long-term follow-up.
Main Methods:
- Systematic review adhering to PRISMA guidelines.
- Literature search conducted on PubMed and Embase databases.
- Risk of bias assessed using the MINOR Score.
Main Results:
- Eight retrospective studies involving 84 children were analyzed.
- Common symptoms include otorrhea, otalgia, and recurrent otitis; pituitary involvement with diabetes insipidus was noted.
- CT scans showed osteolytic lesions; MRI aided in detecting intracranial lesions. Recurrence rate was 20.2%.
Conclusions:
- Management of pediatric TBH necessitates a multidisciplinary strategy.
- Otolaryngologists play a key role in early diagnosis and surgical intervention.
- Long-term follow-up is essential for monitoring recurrences and otological complications.
