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Updated: Sep 18, 2025

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
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The Role of Global Longitudinal Strain in Detecting Early Left Ventricular Dysfunction in Pediatric Bicuspid Aortic

Mohammed A Mashali1,2, Isabelle Deschênes1, Carl V Leier3

  • 1Department of Physiology and Cell Biology, Dorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.

Children (Basel, Switzerland)
|June 26, 2025
PubMed

Insights

Global longitudinal strain (GLS) measured by speckle tracking echocardiography (STE) detects early left ventricular (LV) dysfunction in children with bicuspid aortic valve (BAV). This sensitive method aids in monitoring cardiac health in these patients.

Area of Science:

  • Cardiology
  • Pediatric Cardiology
  • Echocardiography

Background:

  • Bicuspid aortic valve (BAV) is a common congenital heart defect.
  • Left ventricular (LV) dysfunction can occur in pediatric BAV patients.
  • Early detection of LV dysfunction is crucial for timely intervention.

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