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Exploring Hirsutism: Epidemiology, Associated Endocrinal Abnormalities, and Societal Challenges in GCC-A Narrative
Mohamed Anas Patni1, Rajani Dube2, Subhranshu Sekhar Kar3
1Department of Community Medicine, RAK College of Medical Sciences, RAK Medical and Health Sciences University, Ras Al Khaimah P.O. Box 11172, United Arab Emirates.
International Journal of Molecular Sciences
|June 26, 2025
Summary
Hirsutism (excessive hair growth) is prevalent in GCC countries due to genetics, lifestyle, and cultural factors. Addressing stigma and improving diagnostics are key for better patient outcomes.
Area of Science:
- Endocrinology
- Genetics
- Public Health
Background:
- Hirsutism, marked by excessive terminal hair, causes medical and psychosocial issues in Gulf Cooperation Council (GCC) countries.
- Regional factors like consanguinity, obesity, and lifestyle increase hirsutism and polycystic ovary syndrome (PCOS) prevalence.
Purpose of the Study:
- To review hirsutism epidemiology, pathophysiology, cultural factors, and management in the GCC.
- To highlight diagnostic challenges and the need for region-specific approaches.
Main Methods:
- Narrative review of existing literature on hirsutism in the GCC.
- Analysis of epidemiological, endocrine, molecular, and cultural aspects.
Main Results:
- High hirsutism prevalence linked to regional factors and cultural stigma delaying care.
- Androgen excess, genetic susceptibility, and epigenetic factors contribute to pathophysiology.
- Current management relies on pharmacological, cosmetic, and traditional therapies with diagnostic limitations.
Conclusions:
- Culturally sensitive research, public awareness, and advanced diagnostics are crucial for improved hirsutism management in the GCC.
- Policy development and healthcare practice guidance are needed.
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