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Strontium-Substituted Calcium Orthophosphates: Structure, Stability, Morphology, and Biomedical Applications.
1Department of Chemistry "Giacomo Ciamician", Alma Mater Studiorum-Università di Bologna, Via Gobetti 85, 40129 Bologna, Italy.
International Journal of Molecular Sciences
|June 26, 2025
Summary
Strontium substitution in calcium orthophosphates enhances bone remodeling. This review covers strontium
Area of Science:
- Biomaterials Science
- Inorganic Chemistry
- Bone Biology
Background:
- Strontium ions show promise for bone remodeling.
- Calcium orthophosphates are key biomaterials.
- Understanding strontium's role is crucial for bone repair.
Purpose of the Study:
- To review current knowledge on strontium substitution in calcium orthophosphates.
- To examine the effects of strontium on material properties.
- To assess the impact on bone biomaterials.
Main Methods:
- Literature review of strontium-calcium orthophosphate studies.
- Analysis of structural, morphological, and stability data.
- Evaluation of biomaterial applications in bone regeneration.
Main Results:
- Strontium substitution alters calcium orthophosphate structure and morphology.
- Material stability is influenced by strontium content.
- Strontium-doped materials show potential in bone repair.
Conclusions:
- Strontium substitution offers a viable strategy for enhancing calcium orthophosphate biomaterials.
- Further research is needed to optimize strontium-doped materials for bone regeneration.
- Strontium-substituted calcium phosphates hold significant therapeutic potential.
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