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Predictors of Mortality in Medical ICU Patients: A Retrospective Study in a Tertiary Care Center in Jordan
Tarek Gharibeh1,2, Munir Abu-Helalah2,3, Hussam Alshraideh4,5
1Department of Internal Medicine, Faculty of Medicine, University of Jordan, Amman 11942, Jordan.
Insights
This study identified key predictors of intensive care unit (ICU) mortality, including delayed admission and specific clinical factors. Understanding these ICU mortality predictors can improve patient outcomes.
Area of Science:
- Critical Care Medicine
- Clinical Epidemiology
Background:
- Intensive Care Unit (ICU) mortality rates are a critical measure of healthcare quality.
- Identifying predictors of ICU mortality is essential for improving patient outcomes and resource allocation.
Purpose of the Study:
- To investigate ICU mortality rates and identify clinical and demographic predictors.
- To analyze the influence of factors like age, comorbidities, lab values, and initial scores on patient outcomes.
Main Methods:
- Retrospective observational cross-sectional study of 1323 patients admitted to Jordan University Hospital ICU (Jan 2022 - Dec 2023).
- Data collected included demographics, comorbidities, laboratory values, intubation status, Glasgow Coma Scale (GCS), and APACHE II scores.
Main Results:
- Overall ICU mortality was 34%. Delayed ICU admission (≥6h) affected 77% of patients.
- Lower mortality was seen in patients admitted via the Emergency Department (ED) compared to ward transfers (32% vs 41%).
- Predictors of higher mortality included vasopressor use, ED intubation, lower hemoglobin, higher APACHE II scores, pneumonia, and urosepsis.
Conclusions:
- This study identified significant predictors of mortality in a tertiary hospital medical ICU in Jordan.
- Early identification of high-risk patients based on these factors may guide timely interventions.
Abstract:
Background/Objectives: This study aims to investigate ICU mortality rates and to identify predictors of ICU mortality, focusing on clinical and demographic variables, including age, comorbidities, hemoglobin and creatinine values, intubation in the Emergency department, and Glasgow Coma Scale (GCS) and APACHE II scores at presentation in the Emergency department, and how these factors influence patients' clinical outcomes. Methods: This retrospective observational cross-sectional study analyzed patients admitted to the Jordan University Hospital (JUH) ICU from 1 January 2022 to 31 December 2023. A total of 1323 patients were included, with a mean age of 65 ± 17 years, of whom 442 (34%) died during their ICU stay. Results: A delay of 6 h or more in ICU admission was reported for 77% of the participants. Mortality rates were significantly lower among patients admitted to the ICU through the Emergency department (32%) compared to those transferred from other wards (41%) (p = 0.003). Higher mortality rates were observed among patients on vasopressors and those intubated in the Emergency department, with lower median hemoglobin (Hb) levels, higher APACHE II scores, and pneumonia as the main diagnosis or urosepsis as the secondary diagnosis (p < 0.001). Conclusions: This study identified predictors of mortality in a medical ICU at a tertiary hospital in Jordan.
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