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Efficacy of Ferrous Sulphate in the Management of Iron Deficiency Anemia in Children

Karishma Siraj1, Faryal Naz2, Shabnam Mahsood3

  • 1Pediatrics, Lady Reading Hospital, Peshawar, PAK.

Cureus
|June 26, 2025
PubMed

Insights

Ferrous sulfate effectively treats iron deficiency anemia in children, significantly improving hemoglobin and ferritin levels within three months. This pediatric anemia treatment also revealed a link between low hemoglobin and underweight children.

Area of Science:

  • Pediatric Hematology
  • Nutritional Deficiencies
  • Public Health

Background:

  • Iron deficiency anemia (IDA) is a widespread pediatric health issue impacting growth.
  • Ferrous sulfate is a common IDA treatment, but its pediatric efficacy needs more study.

Purpose of the Study:

  • To assess ferrous sulfate's effectiveness in raising hemoglobin (Hb) and ferritin in anemic children.

Main Methods:

  • A quasi-experimental study involved 108 children (1-8 years) with IDA.
  • Participants received ferrous sulfate for 3 months, with Hb and ferritin measured pre- and post-treatment.

Main Results:

  • Ferrous sulfate significantly increased Hb by 3.11 mg/dl and ferritin by 5.9 ng/ml.
  • Low Hb levels were positively associated with underweight status in children.

Conclusions:

  • Ferrous sulfate is effective for pediatric IDA, improving key blood markers.
  • Further RCTs with extended follow-up are recommended to confirm findings.

Keywords:
efficacyferrous sulfate supplementshemoglobin: hbinternal medicine & pediatricsiron deficiency anemia (ida)serum ferritin

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