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Updated Calcitonin Values for Prediction of Lymph Node Metastasis in Medullary Thyroid Cancer

Ashok R Shaha1, Ian Ganly1, Louise Davies2,3,4,5

  • 1Head and Neck Service, Memorial Sloan Kettering Cancer Center, New York, New York.

JAMA Otolaryngology-- Head & Neck Surgery
|June 26, 2025
PubMed
Abstract

No abstract available in PubMed .

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Calcitonin, a vital polypeptide hormone, regulates calcium levels within body fluids. It is released by the parafollicular cells, also known as C cells, situated in the follicular epithelium of the thyroid gland. Calcitonin responds to fluctuations in blood calcium levels and the influence of gastrointestinal hormones like gastrin and cholecystokinin.
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
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