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Updated: Sep 18, 2025

Isolation and Quantification of Botulinum Neurotoxin From Complex Matrices Using the BoTest Matrix Assays
Published on: March 3, 2014
[Food-induced Botulism - Diagnosis, treatment and course]
Tim Schröder1,2, Alexey Saranov3
1Zentrale Notaufnahme, Johanna-Etienne-Krankenhaus gGmbH, Neuss, Germany.
Abstract:
A 56-year-old male patient was presented to the neurology department of the emergency unit by the ambulance service with progressive gait instability, dysarthria and gastrointestinal symptoms. Clinical findings also included bilateral mydriasis, asymmetric bilateral ptosis, proximal paresis of the upper extremity and marked dry mouth. Imaging was unremarkable, but the differential diagnosis revealed evidence of a neurotoxic cause. The history of recent consumption of preserved food and the characteristic symptoms quickly led to a suspected diagnosis of foodborne botulism. After early administration of antitoxin and intensive medical treatment with temporary invasive and non-invasive ventilation, the patient was discharged after 14 days without residual neurological impairment.
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