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Public perspectives on 3D printed medications: Insight for formulation design and regulatory development
1Department of Pharmaceutics, College of Pharmacy, Najran University, Saudi Arabia.
Summary
Public awareness of 3D printing in medicine is growing, but acceptance of 3D printed drugs hinges on regulatory approval and scientific validation. User preferences for personalized dosing and safety features are key for patient-centered pharmaceutical development.
Area of Science:
- Pharmaceutical Sciences
- Biotechnology
- Materials Science
Background:
- Three-dimensional (3D) printing offers innovative potential for personalized pharmaceutical dosage forms.
- Understanding public perception is crucial for the clinical and industrial adoption of 3D printed medications.
Purpose of the Study:
- To assess public awareness, preferences, and trust in 3D printed medications.
- To identify predictors of acceptance for patient-centered drug product development.
- To inform pharmaceutical formulation and regulatory strategies.
Main Methods:
- A cross-sectional survey was conducted with 1,299 participants in Saudi Arabia.
- Assessed awareness of 3D printing in healthcare and pharmaceuticals.
- Evaluated perceived benefits, risks, willingness to use, and design preferences for 3D printed drugs.
Main Results:
- 73% were aware of 3D printing in healthcare; 41.7% recognized its role in medicine production.
- Personalized dosing, polypill functionality, and regulatory approval were highly anticipated benefits.
- Regulatory approval and scientific validation were the strongest predictors of acceptance (p > 0.001).
- Usability features like child/elderly-friendly forms and time-indicator markings were prioritized.
Conclusions:
- Public acceptance of 3D printed medications is influenced by trust in regulatory approval and scientific validation.
- Incorporating user preferences into design can enhance medication adherence and therapeutic acceptability.
- Findings guide formulation scientists and regulators in developing patient-centered 3D printed dosage forms.
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