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Related Experiment Videos

Digital necrosis: a paraneoplastic syndrome.

M Petri, K H Fye

    The Journal of Rheumatology
    |August 1, 1985
    PubMed
    Summary

    A 62-year-old man experienced digital necrosis, initially resembling Wegener's granulomatosis. Lung adenocarcinoma was discovered, highlighting a rare association between digital necrosis and internal malignancy.

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    Area of Science:

    • Oncology
    • Pulmonology
    • Vascular Medicine

    Background:

    • Digital necrosis is a rare presenting symptom of internal malignancy.
    • Wegener's granulomatosis is an autoimmune condition that can cause digital necrosis.

    Observation:

    • A 62-year-old male presented with digital necrosis.
    • The clinical presentation mimicked Wegener's granulomatosis.

    Findings:

    • Open lung biopsy revealed adenocarcinoma of the lung.
    • This represents the fifth reported case of lung cancer presenting with digital necrosis.

    Implications:

    • This case underscores the importance of considering internal malignancy in patients with digital necrosis.
    • The unusual association warrants further investigation into the pathomechanisms linking digital necrosis and lung adenocarcinoma.