Related Experiment Video
Updated: Sep 18, 2025

07:22
Measuring the Motor Aspect of Cancer-Related Fatigue using a Handheld Dynamometer
Published on: February 20, 2020
5.9K
Handgrip Strength, Depression, Dementia, Cognitive Function, and Their Predictive Effect on Functional Independence
Juan Antonio Campos-Gutiérrez1,2, Enrique Diaz De León-González3, Hugo Gutiérrez Hermosillo4,5
1Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey, Monterrey 64700, Mexico.
Medicina (Kaunas, Lithuania)
|June 27, 2025
Summary
Cognitive function, left-hand grip strength, and reduced depression are key predictors of functional independence in older adults. These factors help maintain daily living activities as people age.
Area of Science:
- Gerontology
- Neurology
- Public Health
Background:
- Global demographic shifts indicate a growing elderly population with increasing age-related comorbidities.
- Healthcare providers need to identify factors influencing functional independence in older adults for effective care.
- Maintaining independence in activities of daily living is crucial for the quality of life in aging populations.
Purpose of the Study:
- To determine the predictive effect of handgrip strength (left and right), depression, and cognitive function on functional independence in older adults.
- To investigate the relationship between specific health variables and the ability of elderly individuals to perform daily activities.
Main Methods:
- A predictive cross-sectional study design was employed with 84 physically independent older adults.
- Standardized instruments were used: Geriatric Depression Scale, Hachinski Ischemic Scale, Mini-Mental State Examination (MMSE), and Barthel Index.
- Handgrip strength was measured using a 90-kg hydraulic dynamometer.
Main Results:
- Multiple regression analysis revealed that cognitive function, left-hand grip strength, and lower depression levels significantly predict functional independence.
- These factors collectively explained 34% of the variance (R² = 0.34) in activities of daily living.
- The study included participants with a mean age of 84.89 years, with 58.8% being female.
Conclusions:
- Cognitive function, left-hand grip strength, and depression are significant predictors of functional independence in older adults.
- Interventions focusing on cognitive stimulation, physical activity, and managing depression are recommended to enhance functional independence.
- Larger sample sizes are needed to confirm findings and inform robust intervention design.

