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Porcine As a Training Module for Head and Neck Microvascular Reconstruction
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Determinants Associated With Pesticide Exposure in Patients With Head and Neck Cancer: Protocol for a Systematic
Gustavo Adolfo Sánchez-Ramírez1, Manuel López Cabanillas Lomelí2, Blanca Edelia González-Martínez2
1Universidad Autónoma de Nuevo León, Facultad de Odontología, Monterrey, Nuevo León, Mexico.
JMIR Research Protocols
|January 26, 2026
Summary
This systematic review outlines the methodology for investigating head and neck cancer (HNC) linked to pesticide exposure. It aims to synthesize evidence on determinants, establishing a clear protocol for future research in this public health concern.
Area of Science:
- Environmental Health
- Oncology
- Epidemiology
Background:
- Head and neck cancer (HNC) linked to pesticide exposure is a global health issue.
- Specific determinants of this association remain unclear.
- Limited scientific evidence hinders systematic reviews on this topic.
Purpose of the Study:
- To outline a systematic review methodology.
- To explore scientific evidence on determinants of HNC associated with pesticides.
- To establish a rigorous protocol for future research.
Main Methods:
- Adherence to PRISMA-P guidelines for systematic review protocols.
- Comprehensive literature search across multiple databases (PubMed, Embase, Scopus, Web of Science, CINAHL, LILACS, AGRICOLA).
- Inclusion of studies on human participants, regardless of language, with defined eligibility criteria for study design, population, exposure, and outcomes.
Main Results:
- Systematic review initiated February 2025; protocol registered.
- Literature search and review are ongoing.
- Full results, including synthesis of determinants, are expected by June 2026.
Conclusions:
- A clear, publicly available methodology is crucial for systematic reviews.
- This protocol ensures replicability and rigor in HNC and pesticide exposure research.
- Standardized methods will advance understanding of environmental health impacts on cancer.
Keywords:
agrochemicalscancer preventionenvironmental risk factorsoccupational exposurerural healthvulnerable populationsMore Related Videos
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