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Related Experiment Video

Updated: Sep 18, 2025

Simultaneous EEG Monitoring During Transcranial Direct Current Stimulation
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[Development of a Multimodal Transcranial Electrical Stimulation System with Integrated Four-Channel EEG Recordings].

Yan Hang1, Chaoyang Wang1, Qi Yin1

  • 1School of Biomedical Engineering, Health Center, Shenzhen University, Shenzhen, 518055.

Zhongguo Yi Liao Qi Xie Za Zhi = Chinese Journal of Medical Instrumentation
|June 27, 2025
PubMed
Summary

This study introduces a four-channel EEG system for personalized transcranial electrical stimulation (TES). The system monitors brain activity in real-time, enabling precise adjustment of TES parameters for improved treatment outcomes.

Keywords:
high-accuracymulti-channel EEG acquisitionmulti-modeneurodiagnosis treatmenttranscranial electrical stimulation (TES)

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Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Medical Devices

Context:

  • Transcranial electrical stimulation (TES) offers therapeutic potential but lacks personalized treatment approaches.
  • Current methods struggle with real-time brain state monitoring and adaptive parameter adjustment during stimulation.
  • Accurate electroencephalography (EEG) signal acquisition under stimulation interference remains a challenge.

Purpose:

  • To design and validate an integrated four-channel EEG recording multimodal transcranial electrical stimulation system.
  • To enable real-time monitoring and analysis of EEG signals before, during, and after TES.
  • To facilitate personalized TES by allowing physicians to adjust stimulation parameters based on real-time brain states.

Summary:

  • The developed system integrates EEG recording with four TES modes (TACS, TDCS, TPCS, TRNS).
  • It provides real-time EEG monitoring and characteristic analysis for adaptive treatment adjustments.
  • The system achieves precise current output (±2 mA with 0.03 mA accuracy) and dual-frequency stimulation (0-4 kHz and 50-100 kHz), ensuring accurate EEG signals despite interference.

Impact:

  • This system enhances the efficacy of TES treatments by enabling personalized therapeutic interventions.
  • It offers physicians and researchers a tool to better understand brain states and optimize stimulation protocols.
  • The system's accuracy and multimodal capabilities suggest significant potential for clinical application and market adoption.