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Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...

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Association Between Shift Working and Brain Morphometric Changes in Workers: A Voxel-wise Comparison.

Joon Yul Choi¹, Sungmin Kim¹, Yongho Lee²

¹Department of Biomedical Engineering, Yonsei University, Wonju, Republic of Korea.

Safety and Health at Work

|June 27, 2025

Summary

This summary is machine-generated.

Shift work is linked to brain changes, with non-shift workers showing larger cerebellums and shift workers having larger inferior parietal gyri. These findings highlight the impact of occupational environments on brain neuroplasticity.

Keywords:

Brain MRI Neuroplasticity Shift work Voxel-wise comparison

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Area of Science:

Neuroscience
Occupational Health
Radiology

Background:

Observational studies link shift work to health issues.
Neurological evidence of these effects is lacking.
Brain magnetic resonance imaging (MRI) can reveal structural changes.

Purpose of the Study:

To investigate morphometric brain changes in shift workers versus non-shift workers.
To provide brain-based neurological evidence for the health impacts of shift work.
To explore the association between shift work and structural brain alterations.

Main Methods:

111 healthy workers underwent brain MRI.
Voxel-based morphometry analyzed gray matter volume.
General linear models and threshold-free cluster enhancement identified significant differences, controlling for intracranial volume, age, and sex.

Main Results:

Non-shift workers had significantly larger cerebellar regions (p < 0.05).
Shift workers exhibited a significantly larger inferior parietal gyrus.
Both groups showed increased clusters, indicating neuroplasticity.

Conclusions:

Shift work influences brain structure, affecting regions like the cerebellum and inferior parietal gyrus.
Occupational environments, including shift schedules, can impact brain neuroplasticity.
These findings are crucial for occupational health considerations.