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Unusual Sole Extramedullary Diffuse Kidney Involvement in Multiple Myeloma Initial Workup Using 2-[ 18 F]FDG-PET/CT
Bastien Jamet1, Cyrille Touzeau2, Chloe Antier2
1Nantes Université, Univ Angers, CHU Nantes, INSERM, CNRS, CRCI2NA, Médecine Nucléaire, Nantes, France.
Abstract:
2-[ 18 F]fluorodeoxyglucose-positron emission tomography with computed tomography (2-[ 18 F]FDG-PET/CT) in multiple myeloma (MM) allows the detection of extramedullary disease (EMD), which is scarce at initial workup. We report here for the first time uncommon 2-[ 18 F]FDG-PET/CT imaging results of a 63-year-old woman with newly diagnosed MM and sole diffuse kidney EMD revealed by a significantly increased renal volume and intense/diffuse bilateral renal cortical uptake without visualization of the urinary excretory cavities then confirmed by kidney biopsy. This case highlights the possibility of a diffuse organ involvement different from the typical imaging pattern of nodular plasmacytoma lesions in soft tissues.
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