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Resolving the Ambiguity of Complete-to-Partial Point Cloud Registration for Image-Guided Liver Surgery With
IEEE Journal of Biomedical and Health Informatics
|June 27, 2025
Summary
Accurate liver surgery requires precise alignment of preoperative and intraoperative data. A new patches-to-partial matching strategy improves point cloud registration, especially in low-visibility conditions, reducing errors in image-guided procedures.
Area of Science:
- Medical image analysis
- Surgical navigation
- Computer-assisted surgery
Background:
- Image-guided liver surgery relies on accurate alignment of preoperative (CT/MRI) and intraoperative data (point clouds).
- Current semi-automatic alignment methods are prone to errors, necessitating manual correction.
- Correspondence-based point cloud registration offers a fully automatic solution but struggles with limited intraoperative visibility (complete-to-partial ambiguity).
Purpose of the Study:
- To evaluate the performance of state-of-the-art learning-based point cloud registration methods in scenarios with limited intraoperative visibility.
- To propose a novel module to address the complete-to-partial ambiguity in liver surgery registration.
- To improve the accuracy and robustness of point cloud registration for image-guided liver surgery.
Main Methods:
- Evaluation of existing learning-based point cloud registration methods on in silico and in vitro datasets simulating low-visibility conditions.
- Development of a patches-to-partial matching strategy as a plug-and-play module for existing registration frameworks.
- Integration and testing of the proposed module within learning-based registration pipelines.
Main Results:
- State-of-the-art methods showed performance degradation under low-visibility conditions.
- The proposed patches-to-partial matching module significantly reduced registration errors: 6.7 mm (-29%) in silico and 12.5 mm (-40%) in vitro.
- The module outperformed the Lepard method, achieving lower registration errors (9.5 mm in silico, 20.7 mm in vitro).
Conclusions:
- The complete-to-partial ambiguity poses a significant challenge for point cloud registration in image-guided liver surgery.
- The proposed patches-to-partial matching strategy effectively resolves this ambiguity, enhancing registration accuracy in low-visibility scenarios.
- The developed benchmark and module provide a foundation for advancing automated registration in image-guided liver surgery.

