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Related Experiment Video

Updated: Jun 19, 2026

Technical Approach for Infrared Tracking for Soft Tissue Navigation with a Holographic Head-Mounted Display and Preclinical Validation
10:25

Technical Approach for Infrared Tracking for Soft Tissue Navigation with a Holographic Head-Mounted Display and Preclinical Validation

Published on: September 2, 2025

Mixed Reality Surgical Navigation System for Liver Interventions with Comprehensive Validation using Subsurface

Bowen Xiang, Jon S Heiselman, Dingjie Su

    IEEE Transactions on Bio-Medical Engineering
    |June 17, 2026
    PubMed
    Summary
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    This study introduces a mixed reality (MR) surgical navigation platform for liver interventions, featuring soft-tissue deformation correction. The system significantly reduces targeting errors, offering a validated approach for hepatic procedures.

    Area of Science:

    • Medical Imaging and Technology
    • Surgical Navigation Systems
    • Mixed Reality Applications

    Background:

    • Mixed reality (MR) surgical navigation excels with rigid structures but struggles with soft tissue deformation.
    • A gap exists in MR systems with quantitative validation for soft tissue interventions.
    • Intraoperative soft tissue deformation poses challenges for accurate surgical guidance.

    Purpose of the Study:

    • To present a mixed reality (MR) surgical navigation platform for liver interventions.
    • To incorporate soft-tissue deformation correction and real-time probe visualization.
    • To establish a standardized protocol for validating subsurface targeting accuracy in MR systems.

    Main Methods:

    • Developed a comprehensive MR surgical navigation platform with novel soft-tissue deformation correction.

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    Related Experiment Videos

    Last Updated: Jun 19, 2026

    Technical Approach for Infrared Tracking for Soft Tissue Navigation with a Holographic Head-Mounted Display and Preclinical Validation
    10:25

    Technical Approach for Infrared Tracking for Soft Tissue Navigation with a Holographic Head-Mounted Display and Preclinical Validation

    Published on: September 2, 2025

    Three-dimensional Location Approach with Silk Thread Guided Laparoscopic Segmentectomy for Liver Tumor
    06:39

    Three-dimensional Location Approach with Silk Thread Guided Laparoscopic Segmentectomy for Liver Tumor

    Published on: May 23, 2025

  • Implemented real-time microwave (MW) probe trajectory visualization and distance-to-target measurement.
  • Established a standardized experimental protocol for validating subsurface targeting accuracy.
  • Main Results:

    • Achieved clinically viable efficiency with a navigation-to-target time of 5.5 ± 1.3 minutes per session.
    • Non-rigid registration method (NRM) reduced targeting error by 41.3% compared to rigid registration (RRM).
    • Demonstrated a 42.3% reduction in ground-truth measured targeting error using NRM.

    Conclusions:

    • The developed MR system provides a powerful surgical guidance approach for hepatic interventions.
    • This research establishes the first validation framework standard for MR surgical navigation systems that compensate for soft tissue deformation.