The Corrinoid Model for Dissecting Microbial Community Interactions Across Scales.
Zoila I Alvarez-Aponte, Rebecca R Procknow, Michiko E Taga1
1Department of Plant and Microbial Biology, University of California, Berkeley, California, USA;
Annual Review of Microbiology
|June 27, 2025
Summary
The corrinoid model offers a new way to study microbial communities and their interactions. This vitamin B12 cofactor influences microbial structure and function across various environments.
Area of Science:
- Microbiology
- Environmental Science
- Biogeochemistry
Background:
- Microbial communities significantly impact global nutrient cycling and host health.
- Investigating complex microbial interactions is challenging due to species diversity and metabolic capabilities.
Purpose of the Study:
- To introduce the corrinoid model for studying microbial community interactions across scales.
- To highlight the role of corrinoids (vitamin B12) in shaping microbial communities.
Main Methods:
- Review of existing literature on corrinoid biology and microbial community dynamics.
- Application of the corrinoid model to understand interactions from individual microbes to natural communities.
Main Results:
- Corrinoids, essential cofactors for numerous metabolic processes, are produced by only a subset of microbial species.
- The distribution and utilization of corrinoids act as a key factor influencing microbial community structure and function.
Conclusions:
- The corrinoid model provides a robust framework for investigating microbial community interactions.
- Understanding corrinoid biology at different scales enhances our comprehension of microbial ecosystems and their global impact.
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