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Updated: Sep 17, 2025
Oral Health Assessment by Lay Personnel for Older Adults
Published on: February 2, 2020
Development and evaluation of a quality-of-life questionnaire for patients with orbital malignant tumours
Haihan Yan1, Junlian Lang2, Shaoxiao Yan2
1Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren hospital, Capital Medical University, Beijing, 100730, China.
Background:
Orbital malignant tumours seriously affect the quality of life of patients; however, there is currently no quality-of-life questionnaire for patients with orbital malignant tumours.
Objective:
To develop and evaluate a quality-of-life questionnaire for patients with orbital malignant tumours.
Methods:
A pool of items was generated through a literature search, expert meeting and patient interview. Pre-survey and scale evaluation were performed, the quality-of-life questionnaire for patients with orbital malignant tumours (QLQ-OT) was modified, and the scale was evaluated by measuring the quality of life of 46 patients with orbital tumours.
Results:
The effective rate of QLQ-OT was 97.4%, the Cronbach's alpha coefficient was >0.6, and the test-retest reliability Intraclass Correlation Coefficient was >0.7, suggesting good internal consistency and test-retest reliability. The Pearson correlation coefficients were >0.8 between individual domain scores; > 0.6 between items and their own domains in the QLQ-OT; and >0.6 between domains and their corresponding domains in Quality of Life Center Questionnaire, thereby indicating good content, convergent and criterion-related validity. Ten principal components (the initial eigenvalues >1) were abstracted from 38 items of the general by factor analysis, accounting for 81.0% of cumulative variance.
Conclusions:
QLQ-OT has good compliance, reliability, validity and responsiveness and can be used to measure the quality of life of patients with orbital malignant tumours.
