Laparoscopic liver parenchymal transection using CUSA versus harmonic scalpel: a protocol for a prospective...

Area of Science:

• Hepatobiliary Surgery
• Minimally Invasive Surgery
• Surgical Technology Evaluation

Background:

• Harmonic scalpel (HS) and cavitron ultrasonic surgical aspirator (CUSA) are key techniques for liver parenchymal transection (LPT).
• Current guidelines recommend HS for superficial LPT and CUSA for deep LPT in laparoscopic liver resection (LLR).
• The efficacy and safety of using HS for deep LPT in LLR are not well-established.

Purpose of the Study:

• To investigate the feasibility, safety, and efficiency of HS for deep LPT in LLR.
• To compare HS with CUSA for deep LPT in LLR.
• To provide clinical evidence for optimal LPT device selection in LLR.

Main Methods:

• A randomized controlled trial (RCT) protocol for LLR patients.
• Participants will be randomized to either the HS group or the CUSA group.
• Primary outcome: intraoperative blood loss. Secondary outcomes include operative time, conversion rate, and postoperative outcomes.

Main Results:

• This section is not applicable as the abstract describes a study protocol, not results.
• The study is designed to collect data on intraoperative blood loss, transection velocity, operative time, and patient recovery.
• Subgroup analysis will be performed for patients with liver cirrhosis.

Conclusions:

• This RCT aims to clarify the clinical utility of HS for deep LPT in LLR.
• The findings are expected to inform clinical decision-making regarding LPT device selection.
• The study protocol has ethical approval and is registered in the Chinese Clinical Trial Registry.